BrØnsted Reusable Acidic Ionic Liquids Catalyzed Biginelli Reaction under Solvent-Free Conditions

Abstract

2-Pyrrolidonium hydrogensulfate, N-methyl-2-pyrrolidonium hydrogensulfate, and N-methyl-2-pyrrolidonium dihydrogenphosphate as Brønsted reusable acidic ionic liquids (ILs) catalyzed the preparation of 3,4-dihydropyrimidin-2(1H)-one (thione) derivatives from ethyl/methyl acetoacetate, urea/thiourea, and aromatic aldehydes under thermal solvent-free conditions.

GRAPHICAL ABSTRACT

Keywords:

• Biginelli reaction
• ionic liquid
• catalyst
• solvent-free
• aldehyde

Acknowledgments

The authors are thankful to the University of Sistan and Baluchestan Research Council for the partial support of this research.