1,3,2,4-Diazadiphosphetidine-based phosphazane oligomers as source of P(III) atom economy reagents: Conversion of epoxides to vic-haloalcohols, vic-dihalides, and alkenes in the presence of halogen sources

GRAPHICAL ABSTRACT

Abstract

1,3,2,4-Diazadiphosphetidines (P₁–P₃), as easily prepared, stable, and heterogeneous P(III) compounds, were used for the efficient conversion of epoxides to vic-halohydrins, vic-dihalides, or alkenes in the presence of different halogen sources in CH₃CN. Of these phosphazanes, P₃ is most suitable and contains 4 phosphorous atoms with the advantage of having greater atom economy and its phosphorus oxide byproduct can be easily separated from the reaction mixture by simple filtration. The nitrogen atoms in this molecule can also act as acid scavengers in the reaction.

Keywords:

• 1, 3, 2, 4-Diazadiphosphetidine
• Epoxide
• Halogen
• vic-halohydrin
• vic-dihalide
• alkene