Nitrilotris(Methylenephosphonic Acid) as a New Highly Efficient and Recyclable BrØNested Acid Catalyst for the Synthesis Of Quinoxaline Derivatives under Mild and Green Conditions

GRAPHICAL ABSTRACT

Abstract

Nitrilotris(methylenephosphonic acid) has been introduced as a novel organocatalyst for the preparation of quinoxalines. It can efficiently catalyze the synthesis of quinoxaline derivatives from 1,2-diamines and 1,2-diketones under mild, efficient, and eco-friendly conditions. Excellent yields, very short reaction times, safety, and recyclability of the catalyst system are other features of the proposed method.

Keywords:

• Nitrilotris(methylenephosphonic acid)
• 1,2-diamines
• 1,2-diketones
• quinoxalines
• organocatalyst
• recyclable catalyst