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GRAPHICAL ABSTRACT
ABSTRACT
A wide range of phosphorylated α-,β-,γ-aminoacetals of various structure were obtained by Kabachnik-Fields reaction. Acid-catalyzed reactions of phenols with α-,β-,γ-aminoacetals provide a new approach to the synthesis of different polyphenols, containing aminophosphonate and aminophosphine oxide moieties, arylsubstituted heterocycles containing phosphonate and phosphinoxide groups. Herein we present a short overview of these reactions.
Funding
This work was funded by the Russian Foundation for Basic Research (grant no. 15-43-02088).