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Original Articles

Synthesis of the azapodands with phosphoryl terminal groups

, , , &
Pages 1666-1667 | Received 12 Aug 2016, Accepted 12 Aug 2016, Published online: 02 Sep 2016
 

GRAPHICAL ABSTRACT

ABSTRACT

New lipophilic phosphorylated azapodands with different substituents at the nitrogen atom were synthesized via the Kabachnik–Fields reaction in the three-component system: di-p-tolylphosphinous acid–formaldehyde–1,8-diamino-3,6-dioxaoctane. The reaction was carried out in toluene or acetonitrile media, with p-toluenesulfonic acid acting as a catalyst.

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