108
Views
14
CrossRef citations to date
0
Altmetric
Original Articles

Substrate specific nanoreactors based on pyrimidine-containing amphiphiles of various structures for cleavage of phosphonates

, , , , , & show all
Pages 1673-1675 | Received 18 Aug 2016, Accepted 19 Aug 2016, Published online: 29 Aug 2016
 

ABSTRACT

The series of novel pyrimidine-containing amphiphiles were examined as catalysts for cleavage of phosphonates having various hydrophobicities. Kinetic data showed marked substrate specificity of three different types (i) inhibition for both substrates, (ii) catalysis for more hydrophobic phosphonate and inhibition for less hydrophobic phosphonate, and (iii) catalysis for both substrates. The highest acceleration (more than 11 times in comparison with the reaction in the absence of amphiphile) has been reached in the case of dicationic amphiphile with three hydrophobic tails.

GRAPHICAL ABSTRACT

Funding

This work was financially supported by the Russian Science Foundation (Project No. 14-50-00014).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.