ABSTRACT
This brief review describe the recent advances in using oxamic acid thiohydrazides as precursors for the formation of hydrazones intermediates from natural and synthetic compounds bearing a carbonyl group. These intermediates undergo a variety of synthetically useful transformations, which include nucleophilic addition and 6π-electrocyclic reactions to generate new heterocycles.
Funding
The reported study was funded by RFBR and Moscow city Government according to the research project No. 15-34-70030 “mol_a_mos.”