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Short Communication

Improved synthesis of N-sulfonylformamidine derivatives promoted by thionyl chloride

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Pages 485-489 | Received 18 Dec 2016, Accepted 31 Dec 2016, Published online: 15 Mar 2017
 

GRAPHICAL ABSTRACT

ABSTRACT

An improved synthesis of N-sulfonylformamidine derivatives has been developed involving direct condensation of various sulfonamides and formamides in the presence of thionyl chloride using chloroform as solvent. Detailed synthetic studies indicate that this procedure gives the desired products in high yields under mild conditions.

Funding

This work was supported by the National Natural Science Foundation of China (21362038).

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