Synthesis of novel “hybrid” structures based on phosphorylacetic acid hydrazides and sterically hindered phenols

Abstract

The insertion of fragments of sterically hindered phenols into the structure of phosphorylacetic acids hydrazides in their reactions with 3,5-di-tert-butyl-4-hydroxybenzylacetates and sterically hindered 2- and 4-hydroxybenzaldehydes has been carried out. The synthesis of 3,5-di-tert-butyl-4-benzyl derivatives of 5-[(diphenylphosphoryl) methyl]-2,4-dihydro-3H-1,2,4-triazol-3-thiones was also carried out.

GRAPHICAL ABSTRACT

Keywords:

• Sterically hindered phenols
• phosphorylacetic acid derivatives
• hybrid compounds

Acknowledgments

The reported study was funded by RFBR and Government of the Republic of Tatarstan according to the research project № 18-43-160004.