Reactivity of aminophosphonic acids. 2. Stability in solutions of acids and bases

Abstract

The stability of the representative series of ω-aminoalkylphosphonic acids (ω-AA^P: 2-Ala^P and 3-Ala^P), 1-aminoalkylphosphonic acids (AA^P: Gly^P; Ala^P and Pgl^P) and quaternary 1-aminoalkylphosphonic acids (AA^P: Mal^P), 1-(N-alkylamino)alkylphosphonic acids (R-AA^P: tBu-Gly^P; tBu-Ala^P; Me-Hal^P; Et-Hal^P and Et-Mal^P) and 1-(N,N-dialkylamino)alkylphosphonic acids (R₂-AA^P: Me₂-Gly^P and Me₂-Hal^P) being exposed to acidic (2 M H₂SO₄) and/or basic (2 M KOH) solutions in the temperature range of 25-100 °C, was investigated.

Graphical Abstract

Keywords:

• Aminoalkylphosphonic acids
• hydrolytic stability
• degradation