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Original Articles

Catalyst free one-pot synthesis of α-aminophosphonates in aqueous ethyl lactate

, , & ORCID Icon
Pages 528-532 | Received 04 Jul 2018, Accepted 26 Oct 2018, Published online: 18 Dec 2018
 

Abstract

An highly efficient and environmentally friendly process for the synthesis of α-aminophosphonates has been devised, through a one-pot three-component condensation of various aldehydes, amines and triethyl phosphate in water-ethyl lactate under ultrasonic irradiation conditions at room temperature. The expected products were obtained in high yield without the need for any additional catalyst.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

We are grateful for the financial support from the Science and Technology Research Foundation of Hebei Normal University (L2018Z06), the Natural Science Foundation of Hebei Province (B2015205182) and the National Natural Science Foundation of China (21272053).

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