The sulfinyl group: Its importance for asymmetric synthesis and biological activity

Abstract

Most important examples of the application of the sulfinyl moiety as the crucial (essential) group both in chiral enantiomeric ligands/catalysts and in biologically active compounds are selected from the Authors’ works and briefly discussed.

Graphical Abstract

Keywords:

• Sulfoxides
• chiral ligands/catalysts
• asymmetric synthesis
• sulforaphane analogs

Acknowledgments

The Authors are deeply indebted to the researchers from the National Medicines Institute in Warsaw: K. Wiktorska, Z. Chilmonczyk, L. Mielczarek, M. Milczarek, K. Karwowska, and K. Lubelska, for investigations of the antitumor activity of the analogs of sulforaphane.