Foreword for the special issue of phosphorus, sulfur, and silicon and the related elements dedicated to ICPC 22 – 2018

I am happy to introduce this special issue of Phosphorus, Sulfur, and Silicon and the Related Elements, which presents voluntarily submitted papers from the 22^nd International Conference on Phosphorus Chemistry (www.icpc22.mke.org.hu) held in Budapest, Hungary from 8^th–13^th July 2018. The venue for the conference was the Hotel Flamenco located in the heart of the Buda part of Budapest (Figure 1). It was a great honor for us, as Hungarian organophosphorus chemists, to have the pleasure of organizing this prestigious event in Hungary.

Figure 1. The venue of ICPC 22.

ICPCs are always highly-ranked events held in the past every 3 years, and biannually, more recently. Prestigious gatherings, such as this one remain in great demand, and represent a continuum of high quality during a time when we receive many invitations to predatory conferences. ICPCs are indeed different kinds of events. My first such conference was the 10^th ICPC in Bonn organized by Professor Appel, in 1986. It was followed by the meetings in Tallin (Prof Veiderma), Toulouse (J.-P. Majoral and G. Bertrand), Jerusalem (É. Breuer), Cincinnati (F. Ebetino and C. McKenna), Sendai (M. Joshifuji and T. Kawashima), Birmingham (P. Metevier), Xiamen (Jufen Zhao), Wrocław (P. Kafarski), Rotterdam (K. Lammerstma), Dublin (D. Gilheany) and Kazan (O. Sinyashin and A. Karasik). So we could greet nine previous chairmen!

ICPCs always have a family atmosphere with the majority of participants knowing each other well. Yet we are warm and welcoming to new colleagues especially students and junior researchers. Furthermore, there are a few colleagues from the first generation of the ICPC participants. Unfortunately, some of our cherished and prominent colleagues have passed away in the last decade including Pascal le Floch, Irina Odinets, Stefan Jankowski, Reinhard Schmutzler, Rolf Appel, John Verkade, Juri Gololobov, Jan Mihalski, Harry Hudson and Imre Petneházy. These colleagues were all distinguished organophosphorus chemists. This conference was arranged in memory of Professor Imre Petneházy, the founder of Hungarian organophosphorus chemistry. The senior participants above 50 and below 65 belong to the second generation of attendees. It is very important to see the young generation of OP chemists. It is an important challenge for the Steering Committee to make ICPCs attractive for younger and experienced colleagues so that a diverse array of representatives from all aspects of organophosphorus chemistry are both welcome and encouraged to present.

In the Opening ceremony (Figure 2), Andrey Karasik the co-chair of ICPC 21 transferred the symbol (the estafette object) of the conference to the chair of ICPC 22 (Figure 3). Then, Livia Simon-Sarkadi, the chair-woman of the Hungarian Chemical Society briefly introduced the Hungarian Chemical Society. The next speaker was József Nagy, the Dean of the Chemical Engineering and Bioengineering Faculty of the Budapest University of Technology and Economics. The Chair and co-Chair of the Steering Committee of the ICPC, Frank H. Ebetino, and Charles McKenna, respectively, also made their welcoming comments (Figure 4). Then, it was my turn to address the ca. 300 participants from 26 countries, from all over the world including Australia, Austria, Canada, China, Czech Republic, Finland, France, Germany, Hungary, India, Ireland, Israel, Japan, Mexico, Poland, Russia, South Africa, Singapore, Spain, Switzerland, Sweden, the Netherlands, Turkey, UK, US and Ukraine.

Figure 2. Opening ceremony with the speakers.

Figure 3. Transfer of the ‘estafette’ from the previous Co-chair Andrey Karasik to Chair Keglevich.

Figure 4. Co-Chairs of the Steering Committee, Frank H. Ebetino (right) and Charles McKenna (left).

Finally, László Nyulászi (a member of the Scientific Committee) and György Horvai (representative of IUPAC) conveyed their message, followed by the production of a dance group ‘Star Eye’. The message of the perhaps most senior organophosphorus chemist, Louis D. Quin was also read (Figure 5).

Figure 5. The message of Louis D. Quin.

ICPC 22 exhibited 10 invited plenary lectures (Table 1), 40 keynote slots (Table 2), 100 short oral presentations, and ca. 130 posters. Except for the plenaries, the orals were presented in 3 parallel sessions.

Table 1. Plenary lectures.

Name of speaker	Affiliation	Title of lecture/indication of subject area
Anton Vidal		Efficient ligand platforms from our group for the stereoselective formation of C-H, C-B and C-C bonds
Annie-Claude Gaumont	Laboratoire de Chimie Moléculaire et Thioorganique, ENSICAEN, Caen, France	Phosphorus-boron compounds: from structure to versatile reactivity
Paweł Kafarski	Institute of Organic Chemistry University of Wrocław, Poland	Are aminophosphonates still worthwhile to synthesize?
Jean-Luc Montchamp	Department of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas, USA	Challenges and solutions in phosphorus chemistry
Christian Müller	Institut für Chemie und Biochemie -Anorganische Chemie-Freie Universität Berlin, Germany	The multifaceted chemistry of aromatic phosphorus heterocycles
Petro P. Onys’ko	Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine	Imidoyl phosphonates: Novel class of imines for organic synthesis
Christopher D. Spilling	University of Missouri-St. Louis, St. Louis, USA	Synthesis of biologically active phosphorus-containing heterocycles
Dmitry Yakhvarov	A.E. Arbuzov Institute of Organic and Physical Chemistry, Russian Academy of Sciences, Kazan, Russian Federation	Electrochemical methods in phosphorus chemistry: Recent discoveries and perspectives
Shigehiro Yamaguchi	Department of Chemistry, Graduate School of Science, Nagoya University, Furo, Chikusa, Nagoya, Japan	Photostable and near IR phosphorus fluorophores for bioimaging
Marian Mikołajczyk	Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Łódź, Poland	Recalling the memory of Professor Jan Michalski (1922- 2017)

Table 2. Keynote lectures.

Name of speaker	Title of lecture
Bansal, R. K. (IN)	MULTIFACETED CHEMISTRY OF 2-PHOSPHAINDOLIZINES
Budnikova, Y. H. (RU)	OPPORTUNITIES AND CHALLENGES FOR COMBINING ELECTRO- AND ORGANOMETALLIC CATALYSIS IN C(sp^2)-H PHOSPHONATION
Caruthers, M. (US)	OLIGONUCLEOTIDE SYNTHESIS INTERFACED WITH MOLECULAR BIOLOGY AND NANOTECHNOLOGY
Chen, X. (CN)	NEW APPLICATIONS OF H-PHOSPHONATE IN SYNTHETIC METHODOLOGIES
Drabowicz, J. (PL)	SELECTED COMPOUNDS CONTAINING A STEREOGENIC PHOSPHORUS ATOM AS CHIRAL IONIC LIQUIDS, LIGANDS AND/OR ORGANOCATALYSTS
Duan, W.-L. (CN)	CATALYTIC ASYMMETRIC SYNTHESIS OF PHOSPHORUS COMPOUNDS
Ebetino, F. H. (US)	BISPHOSPHONATE CONJUGATE CHEMISTRY FOR BONE TARGETING APPROACHES WITH UTILITY IN BONE RELATED DISEASES
Gates, D. P. (CAN)	HIGHLY FUNCTIONAL ORGANO-PHOSPHORUS MACROMOLECULES WITH UNIQUE PROPERTIES AND FUNCTIONALITY
Gilheany, D. (IE)	ELECTROPHILIC REACTIVITY OF HALO-PHOSPHONIUM SALTS: KINETIC ENHANCEMENT VIA THE HAMMOND POSTULATE, A NARCISSISTIC COUPLE & DIRECT OBSERVATION OF SN2
Grützmacher, H. (CH)	THE CHEMISTRY OF THE 2-PHOSPHAETHYNOLATE ANION
He, Z. (CN)	KUKHTIN-RAMIREZ ADDUCTS-MEDIATED SYNTHESES OF BIOLOGICALLY IMPORTANT HETEROCYCLES
Heinicke, J. (DE)	π-EXCESS-AROMATIC AND NON-AROMATIC 1,3-AZAPHOSPHOLES – THE MULTIPLE REACTIVITY AND IMPACT OF ANNULATION
Hey-Hawkins, E. (DE)	MAKING AND BREAKING OF PHOSPHORUS-PHOSPHORUS BONDS
Hissler, M. (FR)	AGGREGATION-INDUCED EMISSION ORGANOPHOSPHORUS COMPOUNDS FOR OPTO-ELECTRONIC APPLICATIONS
Hodgson, D. R. W. (UK)	CHEMO-ENZYMATIC PREPARATION OF NUCLEOSIDE TRIPHOSPHATES FROM DIPHOSPHATES USING FEEDSTOCK CHEMICALS
Kalchenko, V. (UKR)	CHIRAL PHOSPHORUS-CONTAINING CALIXARENES
Karaghiosoff, K. (DE)	FUNCTIONALIZED PHOSPHINES FASCINATING NEW MOLECULES WITH EXCITING CHEMISTRY
Karasik, A. (RU)	LUMINESCENT COMPLEXES ON A SCAFFOLD OF P2N2-LIGANDS. DESIGN OF MATERIALS FOR ANALYTICAL AND BIOMEDICAL APPLICATIONS
Keglevich, G. (HU)	THE BENEFITS OF MICROWAVE ASSISTANCE IN CATALYTIC REACTIONS WITHIN ORGANOPHOSPHORUS CHEMISTRY
Kolodiazhnyi, O. (UKR)	STEREOCHEMISTRY OF ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUTION AT PHOSPHORUS
Lammertsma, K. (NL)	CHEMISTRY OF WHITE PHOSPHORUS AND 1,3-P,N-LIGANDS
Lipok, J. (PL)	ENVIRONMENTAL PHOSPHOROMICS AND ITS USEFUL ANALYTICAL TOOLS
Marinetti, A. (FR)	PHOSPHAHELICENES: SYNTHESIS, PROPERTIES AND APPLICATIONS IN ENANTIOSELECTIVE GOLD CATALYSIS
McKenna, C. (US)	BISPHOSPHONATE CONJUGATES IN MEDICINAL CHEMISYRY: VERSATILE MOLECULE PROBES AND DRUG DELIVERY VEHICLES
Mironov, V. F. (RU)	CAGE (P–C/P–O)-PHOSPHORANES: SYNTHESIS, CRYSTAL STRUCTURE AND SOME CHEMICAL PROPERTIES
Nakazawa, H. (JP)	HYDROPHOSPHINATION OF UNSATURATED HYDROCARBONS PROMOTED BY AN IRON COMPLEX
Nyulászi, L. (HU)	π-CONJUGATED PHOSPHORUS COMPOUNDS
Roesky, H. W. (DE)	CHEMISTRY OF COMPOUNDS WITH LOW COORDINATE PHOSPHORUS
Scheer, M. (DE)	FIVE-FOLD SYMMETRIC COMPLEXES FOR SPHERICAL SUPRAMOLECULAR AGGREGATIONS
Stankevič, M. (PL)	β-HYDROXYALKYLPHOSPHINE DERIVATIVES - AN INTRIGUING REACTIVITY
Streubel, R. (DE)	METAL COMPLEXES WITH HIGHLY REACTIVE OPEN-SHELL P-LIGANDS
Swamy, K. C. K. (IN)	NEW ASPECTS OF IODINATION/DEIODINATION AND RELATED REACTIONS INVOLVING ALLENYLPHOSPHONATES/ALLENYLPHOSPHINE OXIDES
Virieux, D. (FR)	DESIGN OF ORIGINALLY SHAPED OR DECORED CHIRAL PHOSPHINES AND PHOSPHINE OXIDES
Werner, T. (DE)	RECENT ADVANCES IN CATALYTIC WITTIG-TYPE REACTIONS BASED ON P(III)/P(V) REDOX CYCLING
Wiemer, A. J. (US)	EVALUATION OF MIXED ARYL PHOSPHOANTIGEN PRODRUGS
Wiemer, D. (US)	INHIBITION OF GERANYLGERANYL DIPHOSPHATE SYNTHASE BY TRIAZOLE BISPHOSPHONATES
Woodward, G. (UK)	INDUSTRIAL PH3 CHEMISTRY AND APPLICATIONS
Xia, H. (CN)	CARBOLONG CHEMISTRY: A NOVEL π-CONJUGATED SYSTEM CONTAINING PHOSPHINE LIGANDS AND PHOSPHONIUM SUBSTITUENTS
Yang, S. (CN)	INNOVATIONS IN CHIRAL ORGANOPHOSPHORUS SYNTHESIS AND APPLICATIONS
Yoshifuji, M. (JP)	STEREOCHEMICAL FEATURES OF LOW-COORDINATE ORGANOPHOSPHORUS COMPOUNDS

There were two special programs provided by fellow chemists. The ‘0^th’ plenary lecture compliments of István Hargittai was entitled ‘Scientific Budapest’, and there was an organ concert in the St. Emerich Church by György Hajós (Figure 6). The excursion and the banquet were merged as an excursion to Visegrád followed by castle games and a nice conference dinner (Figure 7). The participants rode to Budapest by a ship on the River Danube (Figure 8).

Figure 6. An organic chemist, Prof. György Hajós, who played the organ.

Figure 7. Dinner at Visegrád. In the front, Koop Lammerstma and Chris Spilling.

Figure 8. Traveling back to Budapest.

At the closing ceremony (Figure 9), the dates and venues of the next two ICPCs were announced. Hence, ICPC 23 will be held in Ningbo (China) in 2020 to be organized by chair Yan-Mei Li, with honorary chair Yufen Zhao and general secretary Feng Ni (Figure 10). ICPC 24 will take place in Czestochowa (Poland) in 2021 under the chairmanship of Józef Drabowicz with honorary chair Marian Mikołajczyk (Figure 11).

Figure 9. Closing ceremony.

Figure 10. Chairman of ICPC 23, Yan-Mei Li.

Figure 11. Chairman of ICPC 24, Józef Drabowicz.

The award winners of the poster session were then announced. The poster award committee comprised P. Kafarski, M. Yoshifuji and C. Spilling, with E. Bálint as the organizer.

The organizers hope that the new process whereby only the abstracts of the oral lectures were included in the abstract book, and the other extracts were published online was found to be an acceptable compromise.

I would like to thank our title sponsors, Richter Pharmaceuticals, Chinoin–Sanofi, Solvay, EGIS–Servier, Taylor and Francis, Molecules, DeGruyter, and IUPAC for their support and endorsement.

The invaluable help of the Local Organizing Committee and the Scientific Committee is also gratefully acknowledged. As chair of this ICPC, I am indebted to Beáta Androsits and Beatrix Schenker for their assistance. Last but not least, our colleagues who advanced the publication of this special issue should be mentioned. Hence, I warmly thank the Editor-in-Chief Martin Rudd, my Associate Editors Erika Bálint, Nóra Zs. Kiss and Péter Bagi, along with the Assistant Editors Ádám Tajti, Zita Rádai and Réka Henyecz.

György Keglevich
Chairman of ICPC 22
Guest-Editor