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Original Articles

Synthesis of functionalized selenazole derivatives via a three-component condensation of ethyl-2-chloro-3-oxo-butyrate, potassium selenocyanate and hydrazine or hydrazide derivatives

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Pages 245-248 | Received 11 Aug 2019, Accepted 26 Sep 2019, Published online: 09 Oct 2019
 

Abstract

A simple, one-pot synthesis of five highly functionalized selenazole derivatives has been achieved in moderate-to-good yields via a three-component condensation of ethyl-2-chloro-3-oxo-butyrate, potassium selenocyanate and various substituted hydrazines or hydrazides in acetone at room temperature.

Graphical Abstract

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