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Research Article

Cobalt-catalyzed domino C-N cross-coupling reaction between phenyl(2-halo)isothiourea and aryl halide

, , , &
Pages 559-568 | Received 24 Sep 2020, Accepted 01 Jan 2021, Published online: 27 Jan 2021
 

Abstract

A simple route for the synthesis of 2-aminophenyl benzothiazole through domino intra and inter molecular C-N cross-coupling reaction using a cobalt catalyst under mild reaction conditions has been accomplished. The procedure is experimentally simple, general, and efficient. All the substrates readily carried out under optimized reaction conditions to provide target products in moderate to good yield.

Graphical Abstract

Acknowledgment

Authors thank GITAM University, Hyderabad for providing the laboratory to carry out the experimental work.

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