SOME REACTIONS OF 2-MERCAPTO-3,5,7-TRIPHENYLPYRIDO[2,3-d]PYRIMIDINE-4(3H)-ONE SYNTHESIS OF PYRIDOTRIAZOLO AND PYRIDOTETRAZOLOPYRIMIDINE DERIVATIVES

Abstract

Treatment of 2-Mercapto-3,5,7-triphenylpyrido[2,3-d]pyrimidine-4(3H)-one (I) with hydrazine hydrate afforded 2-hydrazino derivative II. Compound II underwent ring closure with formic acid and/or triethyl orthoformate, acetic anhydride and/or acetyl chloride and other different reagents to give the title compounds.

Key Words:

• Mercaptopyridopyrimidine
• pyridotriazolo
• pyridotetrazolopyrimidine