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Original Articles

SYNTHESIS AND CLEAVAGE REACTIONS OF BENZOTHIAZEPINYL CHROMONE DERIVATIVES

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Pages 143-147 | Received 12 Aug 1988, Accepted 17 Oct 1988, Published online: 04 Oct 2006
 

Abstract

A few benzothiazepinyl chromones (II & IV) were prepared by the reaction of 2-amino benzenethiol with new types of chromonyl chalcones (I & III). One representative compound (IVb) was cleaved with hydrazine hydrate and with hydroxylamine hydrochloride to afford pyrazole (V) and isoxazole (VI) derivatives. The structures of these compounds were confirmed by their analytical and spectral analysis. Some of the above compounds were screened for their anti-microbial activity.

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