Eight-Membered Phosphorus Heterocycles: Synthesis, Three-Dimensional Structure and Stereoelectronic Effects

Abstract

General conclusions on three-dimensional structure of 8-membered phosphorus rings are given in terms of the effects produced by the exo- and endo-cyclic heteroatoms, planar fragments, their number and localization. The role of anomeric effect in determination of exocyclic substituent orientation in 6-, 7-and 8-membered cycles is considered. The influence of stereoelectronic interactions in the conformational behavior as well as further prospects in this expanding field are discussed.