Phosphorus-Containing N'-Trifluoromethylcarbodiimides and N'-Trifluoromethylfluoroformamidines in Reactions with Nucleophilic Reagents

Abstract

The presence of highly reactive fluorine containing grmps in molecules of phosphorus compounds results in un-usual and unpredictable chemical properties of these compounds. This work describes the synthesis and chemical properties of ealier unknown phosphorus-containing N'-tri-fluoromethylcarbodiimides and N'-trifluoromethylfluoroform- midines. The studied conversions of these compounds allowed us to develop the new approaches to the synthesis of fluorine containing a-aminoalkylphosphorylic compounds, which have drawn attention of researchers in the field of physiologically active substances in last years.