Abstract
Me/P(X)C12 (X,Y = O,S) reacts with equimolar as well as with excess amounts of pyridine below room temperature to form pyridinium betaines which act as strong bifunctional phosphorylating agents, Isolation of quite stable crystalline betaines can be accomplished by using 4-dimethylaminopyridine. The concept of donor-mediated phosphorylation is also applioable to monofunctional systems and oan even be made more convenient by in situ generation of the reagents.