REACTIONS WITH HETEROCYCLIC DIAZONIUM SALTS: SYNTHESIS OF SEVERAL NEW THIAZOLO[2,3-c]AS-TRIAZINES AND THIAZOLO [2,3-c] 1,2,4-TRIAZ OLE DERIVATIVES

Abstract

Several new stable thiazolo[2,3-c]as-triazines could be synthesized via coupling of diazotized aminothiazole with active nitrile reagents. On the other hand, several new thiazolyl hydrazonyl chlorides and thiazolyl pyridazine could be synthesized via coupling of thiazole diazonium sulfate with α-chloro diketone, α-chloro β-ketoester compounds and active methylene reagents. The structural assignments were based on the elemental analysis and IR data.

Key Words:

• Reactions with heterocyclic diazonium salts
• synthesis of thiazolo[2,3-c]as-triazines
• heterocyclic diazonium salts
• synthesis of thiazolo[2,3-c]1,2,4-triazoles
• utility of thiazol-2-yl diazonium sulphate
• synthesis of thiazol-2-yl hydrazonoyl chlorides