One-Pot Conversion of Aldoximes Into Nitriles via Aldoxime Tosylates Under Microwave Irradiation

Silica-gel-supported aldoximes react with tosyl chloride at room temperature to give the corresponding aldoxime tosylates. These supported aldoxime tosylates were directly converted to their corresponding nitriles in high yields under microwave irradiation.

Keywords:

• Aldoximes
• tosylates
• nitriles
• microwave irradiation

Acknowledgments

We are grateful to partial financial support from the Azzahra University Research Council.

Notes

^a Yeilds are based on weight of oximes used.