Al₂O₃/MeSO₃H (AMA) as a New Reagent for the Thia-Fries Rearrangement of Arylsulfonates to Hydroxyaryl Sulfones

A new facile method for thia-Fries rearrangement of arylsulfonates has been developed. A variety of arylsulfonates rearrange in excellent yields in the presence of Al₂O₃/MeSO₃H as a new reagent without the use of any solvent.

Keywords:

• Al₂O₃
• MeSO₃H
• arylsulfonates
• hydroxyaryl sulfones

We gratefully acknowledge the support of this work by the Shiraz University Research Council.

Notes

^a Isolated yields.

^b 65% bis (4-methyl phenyl) sulfone was obtained (Jacobsen rearrangement). ¹⁷