A series of novel sulfide derivatives of expected biological activity were synthesized via the reaction of 4-(chloroacetyl)antipyrine (1) with several sulfur nucleophiles. The quantitatively available 2-aminothiazole derivatives 10 and 11 were coupled with pyrazolopyridinyl and aromatic diazonium salts to furnish a new series of the corresponding pyrazolopyridinylazo and arylazo-thiazole dyes 12 and 13. The reaction of 4-(cyanoacetyl)antipyrine (14) with phenyl isothiocyanate afforded the nonisolable adduct 15, which was used as a precursor for the synthesis of polyfunctionally substituted ketene N,S-acetal, dihydrothiazole, and thiazolidinone ring systems.
Phosphorus, Sulfur, and Silicon and the Related Elements
Volume 181, 2006 - Issue 1
![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related Research Data
New Water-Soluble Duocarmycin Derivatives: Synthesis and Antitumor Activity of A-Ring Pyrrole Compounds Bearing β-Heteroarylacryloyl Groups
Source:
American Chemical Society (ACS)
Synthesis of new 5-thiazolyl azo-disperse dyes for dyeing polyester fabrics
Source:
Elsevier BV
Crystal Structure of 1,5-Dimethyl-4-(2-oxo-1,2-diphenyl-ethylidene amino)-2-phenyl-1,2-dihydro-pyrazol-3-one
Source:
Pleiades Publishing Ltd
アンチピリン誘導体の合成および抗菌性 (第1報)
Source:
Pharmaceutical Society of Japan
Hydrogen Bonded Triple Helical Structure of 3-Hydroxyquinoxaline-2-carboxalidine-4-aminoantipyrine
Source:
Springer Science and Business Media LLC
Synthesis, characterization, and catalytic evaluation of ruthenium–diphosphine complexes bearing xanthate ligands
Source:
Royal Society of Chemistry (RSC)
Versatile 2-amino-4-substituted-1,3-thiazoles: synthesis and reactions
Source:
Informa UK Limited
New azodisperse dyes with thiazole ring for dyeing polyester fabrics
Source:
Elsevier BV
Über einige 4‐Acyl‐Derivate des Antipyrins.
Source:
Wiley
SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME ACRIDINYL AMINO ANTIPYRINE, ACRIDINYL AMINO ANTHRAQUINONE, ACRIDINO THIOUREA AND THIAZOLINO THIOUREA DERIVATIVES
Source:
Informa UK Limited
Linking provided by
