Synthesis of N-(bisphosphonomethyl)-aza-15-Crown-5 and N-(bisphosphonomethyl)-aza-18-Crown-6 Ethers as Artificial Ion Channels: An Approach to Channel-Type Molecular Structures

We report the synthesis and characterization of 2 new N-(bisphosphonomethyl)-aza-15-crown-5 1a and N-(bisphosphonomethyl)-aza-18-Crown-6 ethers 1b designed to further investigate the supramolecular assemblies based on exocyclic functional groups of crown ethers.

Keywords:

• Aza-18-Crown-6 ether
• aza-15-Crown-5 ether
• gem-bisphosphonates
• supramolecular assemblies

We are very grateful to Professor H. GROβ, who drawed our attention to the potential interest of structures such as 1 .