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Original Articles

THE PREPARATION AND REARRANGEMENT OF 3- PYRIDYL-4-ALKYL (OR ARYL)-1,2,4- OXADIAZOLE-5 (4H)-THIONES

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Pages 47-51 | Received 26 Mar 1991, Accepted 07 May 1991, Published online: 23 Sep 2006
 

Abstract

3-Pyridyl-4-alkyl (or aryl)-1,2,4-oxadiazole-5(4H)-thiones are prepared by the reaction of N-alkyl (or aryl) pyridine carboxamide oximes with thiophosgene. Rearrangement, catalysed by metallic copper, yields the corresponding 3,4-disubstituted-1,2,4-thiadiazole-5(4H)-ones.

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