REACTION OF SCHIFF'S BASES WITH MERCAPTO ACIDS. SYNTHESIS OF SPIRO [2H-1,3-BENZOTHIAZINE-2,3′-[3H]INDOLE]-2′,4(1′H,3H)-DIONES AND SPIRO[3H-INDOLE-3,2′-THIAZOLIDINE]-2,4′(1H)-DIONES

Abstract

The synthesis of some new sulfur containing spiroindole derivatives is reported. Spiro[2H-1,3-benzothiazine-2,3′-[3H]indole]-2′,4(1′H,3H)-diones and spiro[3H-indole-3,2′-thiazolidine]-2,4′(1H)-diones were prepared by the reaction of 3-[2-(4-arylthiazolylimino)]-1,3-dihydro-2H-indol-2-one with o-mer-captobenzoic acid and mercaptoacetic acid respectively. Such spiro benzothiazineindoles are being reported for the first time. The compounds have been characterised on the basis of elemental and spectral studies.

Key Words:

• Spiroindole derivatives
• mercapto acids
• NMR
• IR