SYNTHESIS AND LAXS INVESTIGATION OF SOME 1-(D-3-MERCAPTO-2-METHYLPROPIONYL)-L-PROLINE AMORPHOUS COMPLEXES WITH C₀(II), Ni(II), Zn(II), Cd(II)

Abstract

Four amorphous metal complexes with 1-(D-3-mercapto-2-methylpropionyl)-L-proline (L) with general formula Na₂ML₂·nH₂O (M = Co, n = 14; M = Ni, n = 4; M = Zn, n = 4; M = Cd, n = 7) have been synthesized. LAXS (large angle X-ray scattering) provided information on the local order around the metal(II) ions. A 2:1 ratio between ligand and all examined metal ions was found. A tetrahedral configuration around zinc and cadmium ions has been found with two sulphur and two amidic oxygen atoms bonded to the metals. For nickel and cobalt complexes an octahedral configuration has been found with two water molecules bonded to the metal in axial position and two ligand molecules bonded via sulphur and amidic oxygen in equatorial position.

Key Words:

• 1-(D-3-mercapto-2-methylpropionyl)-L-proline complexes
• captopril-metal complexes
• large angle X-ray scattering