NOVEL SULFUR CONTAINING AGRO CHEMICALS: SYNTHESIS OF MERCAPTOTRIAZOLES, TRIAZOLO-(3,4-b)-THIADIAZOLE, TRIAZOLO-(3,4-b)-THIADIAZINE AND TRIAZOLO-(3,4-b)-THIADIAZEPINE RING SYSTEMS AS POSSIBLE FUNGITOXIC AGENTS

Abstract

A series compounds II–XII have been synthesized from the stereo-isomeric 4-{4-(Z)-[p-(benzenesul-fonyloxy)phenylmethylene]-5-oxo-1- phenyl-2-imidazolin-1-yl)-benzoic acid hydrazide derivative (I) in order to investigate the fungitoxic activity of the compounds against Rice blast pathogen “Pyricularia oryzae” and Brown leaf spot pathogen “Helminthosporium oryzae” and the possibility of their use as new sulfur-containing agro chemicals. Fungitoxicity of most of the synthesized products compared well with a standard commercial fungicide. The assigned structures for these potential fungitoxic agents were established by elemental analyses, spectral data and whenever possible by alternative synthetic routes.

Key Words:

• Synthesis
• fungitoxicity
• imidazolyl-mercaptotriazoles
• triazolo-(3,4-b)-thiadiazole
• Triazolo-(3,4-b)-thiadiazine
• triazolo-(3,4-b)-thiadiazepine ring systems