Abstract
The title compounds, Z- and E-(2-aryl-3-arylsulfonylcyclopropyl)benzyl sulfones (V & VI) and E,Z- and E,E-bis(2-aryl-3-arylsulfonylcyclopropyl) sulfones (XI & XII) have been prepared by the reaction of aryl thiocarbenes with Z- and E-styryl benzyl sulfones (I & II) and E,Z- and E,E-bis(styryl) sulfones (VII & VIII) under phase transfer conditions. The geometry of the substrates was found to be retained in the product formation as is evidenced by the PMR spectra, thus, confirming the stereospecificity of the reaction. The bioactive nature of the newly synthesized compounds was assayed.