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Abstract
The synthesis of different 3-acetamido-coumarin-6-sulphonylamino acids 2a-e; corresponding methyl esters 3a-e; dipeptides 4a-e and some related 3-amino or 3-hydroxy derivatives 5a-6d are described. All the 3-amino or 3-hydroxycoumarin-6-sulphonylamino acid derivatives were found to possess remarkable antimicrobial properties towards different microorganisms.