SYNTHESIS AND CHARACTERIZATION OF AMINOPYRIDIN-2-YL-METHYL-PHOSPHONIC ACIDS

Abstract

Amino-phosphonic acids and their diethyl esters containing one or two pyridyl moieties were synthetized in good yields, starting from the corresponding Shiff base as precursors. The new compounds were characterized by ¹H- and ³¹P-NMR spectroscopy and preliminary results indicate that they are able to complex with transition metals. Therefore, such compounds can be of utility in diagnostic medicine, NMR imaging and in agrochemistry.

Key Words:

• Amino-pyridylmethyl mono- and di-phosphonate esters
• amino-phosphonic acids
• NMR spectroscopic properties
• chelating agents.