KETOKEN GEM-DITHIOLS AND TRITHIONES: SYNTHESIS AND STUDY OF THE BEHAVIOR TOWARDS DIPOLE REAGENTS; SYNTHESIS OF SOME NITROGEN HETEROAROMATICS

Abstract

The behavior of ketoken gem-dithiols towards active methylene and methyl groups resulted in the formation of thiopyrano-dihydrocaumarine derivatives IIIa, b via cyclocondensation reaction between substituted 4-dihydrocyclohexanone Ia, b. N-phenylpyrazoline derivative VI was also formed through reaction of gem-dithiol IV with malonic acid followed by phenyl hydrazine. Pyridopyridazine derivative XII could also synthesized. The behavior of thione group in XV towards some dipole systems was also investigated to give spiro products XVIII-XX.

Key Words:

• Ketoken gem dithiols
• trithions and dipole reagents
• nitrogen heteroaromatics from gem dithiols