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Abstract
Phthalides 1 have been thiocarbamoylated. We were able to isolate and characterize different reaction products formed by treatment of a mixture of 1 and phenyl isothiocyanate with various amounts of base. 3-Oxo-1,3-dihydro-isobenzofuran-1-carbothioic acid phenylamide 3, 3-{[(1-oxo-3H-isobenzofuranylidene)-phenylamino-methylenethio]methylthio-phenylamino-methylene}-3H-isobenzofuran-1-one 4, 3-oxo-N,1-diphenyl-1,3-dihydro-isobenzofuran-1-carboximidothioic acid methyl ester 5, 3-alkylthio-4-hydroxy-2-phenyl-2H-isoquinolin-1-one 6, and 3-oxo-N,N-diphenyl-3H-isobenzofuran-1,1-dicarboximidothioic acid dimethyl ester 7 were obtained. X-ray studies have been performed in order to identify unequivocally the reaction products.