STUDIES WITH ARYLAMINOMETHYLBENZIMIDAZOLETHIOLS: NOVEL SYNTHESIS OF 1,3-DIAZEPINO- AND 1,2,4-TRIAZEPINO[1,2-a] BENZIMIDAZOLE DERIVATIVES

Abstract

The reaction of 3-(p-substituted arylaminomethyl)benzimidazole-2-thiols la,b with tetracyanoethylene (TCNE) afforded 1,3-diazepino[1,2-a]benzimidazole derivatives 8. 2-Hydrazinobenzimidazole 2 reacted with TCNE and dicyanomethyleneindane-1,3-dione (CNIND) to form 1,2,4-triazepino[1,2-a]benzimidazole derivatives 17 and 18.

Key Words:

• (Arylaminomethyl)benzimidazolethiols
• TCNE
• CNIND
• 1,3-diazepino[1,2a]benzimidazole