Phosphorylated Bromonitroethene in the Reactions with NH- and CH- Acids

Abstract

The interaction between O,O-di(2-dichloroethyl)-2- bromo-2-nitroethenephosphonate and some NH- and CH-acids is discussed.

The highly reactive halonitroethenes attract the attention of scientists so as they are active synthons in the synthesis of various classes of organic compounds. Phosphorylated halonitroethenes can represent particular interest, because of phosphoryl group introduction “a priori” makes the reactivity of such compounds to be higher and allows to synthesize a big number of biologically active compounds. The very first study of interaction between O,O-di(2-chloroethyl)-2-nitroethenephosphonate (1)¹ with some representatives of NH-and CH-acids such as anyline, p-toluydine, dimedone, and malonic ester was conducted by our research group.