Advanced search
Publication Cover
Phosphorus, Sulfur, and Silicon and the Related Elements Volume 120, 1997 - Issue 1
Submit an article Journal homepage
24
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Selective Anodic Monofluorination of Sulfur-Containing Heterocycles: Potent Applications towards Pharmaceuticals

Toshio Fuchigami
Pages 343-344 | Published online: 17 Mar 2008
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

Regioselective anodic monofluorination of 3-thiolanones, 1,3-oxathiolanones, and 1,3-dithiolanones was successfully carried out in MeCN containing Et3Nß3HF or Et4NFß4HF as a supporting electrolyte. Among the fluorinated products, 2-benzyl-4,4-dimethyl-2-ethoxycarbonyl-5-fluoro-3-thiolanone was found to possess comparable or even stronger in vitro human type II phospholipase A2 inhibitory activity compared with the known inhibitor, manoalide.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.