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Original Articles

2,6-DIAROYL-3,5-DIARYL-4-METHYLTETRAHYDRO-1,4-THIAZINE-1,1-DIOXIDES - A SYNTHETIC AND STEREOCHEMICAL STUDY

, , , &
Pages 167-173 | Received 19 Feb 1999, Accepted 09 Apr 1999, Published online: 04 Oct 2006
 

Abstract

Conjugate addition of methy lamine over 2,2′-sulfonylbis(1.3-diarylprop-2-en-1-ones) in dimethylformamide gave the hitherto unknown 2.6-diaroyl-3,5-diaryl-4-methyltetrahydro- 1.4-thiazine-1,1-dioxides in very good yields. The same thiazines were also obtained by condensation of bis(aroylmethyl)sulfones with aromatic aldehydes and methylamine. The structure and stereochemistry of the compounds were deduced from elemental analysis and spectral data.

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