Nickel Catalyzed Electrosynthesis of Triorganyl Phosphines from Organic Halides and Chlorophospines

Abstract

One of the important problem in preparative organic chemistry of organophosphorus compounds is the development of new synthetic approaches to compounds with P-C bonds under mild conditions. Particular attention has been given in this area to the synthesis of triorganyl phosphines much used primarily as ligands in metal complexes. Triorganylphosphines can be easily obtained by electroreduction of an organic halide in the presence of mono- or dichlorophenyl phosphine added gradually using a Ni-2,2-bipyridine catalytic system in DMF in an undivided cell fitted with an magnesium or zinc sacrificial anode. The overall reaction is