Synthesis of Nitrogen-Containing 3-Phosphonoalkylcyclohexenones

Abstract

With a view of preparing compounds with potential biological activity and to study structure-activity relationship, the ring and side chain substituted 3-phosphonomethylcyclohexenones were transformed to aminophosphonic acid derivatives using Schmidt, Beckmann and Neber rearrangement reactions.

Keywords::

• 3-Phosphonoalkylcyclohexenones
• Schmidt
• Beckmann and Neber rearrangement