Application of 1-Azidoalkylphosphonates in the Synthesis of Phosphonodipeptides and Other N-Substituted Aminophosphonates

Abstract

Efficient synthesis of diethyl 1-(isothiocyano)alkylphosphonates, and N-derivatives of diethyl 1-aminoalkylphosphonates as well as phosphonodipeptides were developed using diethyl 1-azidoalkylphosphonates as starting materials.

Keywords::

• diethyl 1-azidoalkylphosphonates
• iminophosphoranes
• phosphonodipeptides
• diethyl (N-alkyl) 1-aminoalkylphosphonates
• diethyl 1-(isothiocyano)alkylphosphonates