The Reactivity of Sulfur Nucleophiles in the Substitution Reactions of Nitro Group and Fluorine in Meta-Substituted Arenes

Abstract

It is well known that nitro group and fluorine are the best leaving groups in activated nucleophilic aromatic substitution reactions [1]. Therewith comparing the rate of these reactions with soft sulfur and hard oxygen nucleophiles is a standard method reasonable to predict leaving nitro group and fluorine mobility [2].