Red Cell Aplasia Due to Erythrovirus Parvovirus B19 Infection in a Jehovah's Witness with Post-transplant EBV-induced Aggressive Lymphoma: Management Considerations

Abstract

The refusal of Jehovah's Witnesses to accept blood and blood products often poses a clinical dilemma to present day medicine. We present a case of a Jehovah's Witness who had undergone renal transplantation, only to develop an Epstein-Barr virus associated aggressive lymphoma post-transplant. His condition was further complicated by erythrovirus (parvovirus) B19 infection resulting in red cell aplasia and severe anemia. The management of this difficult clinical situation is discussed together with a review of recommendations for chemotherapy treatment in Jehovah's Witnesses.

• Jehovah's Witness
• Erythrovirus (Parvovirus) B19
• Renal Transplant
• Lymphoma
• Post-transplant Lymphoproliferative Disorder
• Ptld
• Chemotherapy