Expression of ZAP-70 Protein Correlates with Disease Stage in Chronic Lymphocytic Leukemia and is Associated with, but not Generally Restricted to, Non-mutated Ig V_H Status

Soo-Zin Kim Department of Internal Medicine III, University Hospital Frankfurt, GermanyCorrespondence[email protected]

Kai Uwe Chow Department of Pathology, University Hospital Frankfurt, Germany

Natasa Kukoc-Zivojnov Institute of Human Genetics, University Hospital Kiel, Germany

Simone Boehrer Department of Internal Medicine III, University Hospital Frankfurt, Germany

Angela Brieger Department of Pathology, University Hospital Frankfurt, Germany

Susanne Annette Steimle-Grauer Institute of Human Genetics, University Hospital Kiel, Germany

Lana Harder Department of Internal Medicine III, University Hospital Frankfurt, Germany

Dieter Hoelzer Department of Pathology, University Hospital Frankfurt, Germany

Paris Sophokles Mitrou Institute of Human Genetics, University Hospital Kiel, Germany

Eckhart Weidmann Department of Internal Medicine III, University Hospital Frankfurt, Germany

Expression of ZAP-70 Protein Correlates with Disease Stage in Chronic Lymphocytic Leukemia and is Associated with, but not Generally Restricted to, Non-mutated Ig VH Status