Identification of a novel fusion TBL1XR1–PDGFRB in a patient with acute myeloid leukemia harboring the DEK–NUP214 fusion and clinical response to dasatinib

Paulo Vidal CampregherDepartment of Hematology and Clinical Pathology, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil; ;Foundation Medicine, Cambridge, MT; ;Department of Hematology, University of Campinas (Hemocentro - Unicamp), Campinas, São Paulo, Brazil; Correspondence[email protected]

Nathalia da Silva HalleyDepartment of Pediatric, Hospital Israelita Albert Einstein, São Paulo, Brazil;

Gabriela Amaral VieiraDepartment of Hematology and Clinical Pathology, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil;

Juliana Folloni FernandesHematology and Bone Marrow Transplantation Program, Hospital Israelita Albert Einstein, São Paulo, Brazil;

Elvira Deolinda Rodrigues Pereira VellosoHematology Service, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; ;Cytogenetics Laboratories, Hospital Israelita Albert Einstein, São Paulo, Brazil;

Siraj AliFoundation Medicine, Cambridge, MT;

Tariq MughalTufts University Cancer Center, Boston, MA, USA;

Vincent MillerFoundation Medicine, Cambridge, MT;

Cristovão Luis Pitangueira MangueiraDepartment of Hematology and Clinical Pathology, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil;

Vicente OdoneDepartment of Pediatric Oncology, Hospital Israelita Albert Einstein, São Paulo, Brazil;

Nelson HamerschlakDepartment of Hematology, Hospital Israelita Albert Einstein, São Paulo, Brazil

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Acknowledgements

This is a case report. We have obtained consent from the patient for publication, but the study was not evaluated by an Ethics Committee, because it is not necessary for case reports. The patient whose case is described here gave his consent for publication.

Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article online at http://dx.doi.org/10.1080/10428194.2017.1318437.

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Identification of a novel fusion TBL1XR1–PDGFRB in a patient with acute myeloid leukemia harboring the DEK–NUP214 fusion and clinical response to dasatinib

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Identification of a novel fusion TBL1XR1–PDGFRB in a patient with acute myeloid leukemia harboring the DEK–NUP214 fusion and clinical response to dasatinib

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