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Letters to the Editor

Severe COVID-19 infection in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab therapy

Alexis Genthona Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, FranceCorrespondence[email protected]

https://orcid.org/0000-0002-1293-4236

Thibault Chiarabinib Service de Maladies Infectieuses et Tropicales, Saint-Antoine Hospital, Paris, France

Pierre Baylacb Service de Maladies Infectieuses et Tropicales, Saint-Antoine Hospital, Paris, France

Nadia Valinb Service de Maladies Infectieuses et Tropicales, Saint-Antoine Hospital, Paris, France

Tomas Urbinac Médecine Intensive Réanimation, Hôpital Saint-Antoine, Assistance Publique – Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris Cedex 12, France

Jérome Pacanowskib Service de Maladies Infectieuses et Tropicales, Saint-Antoine Hospital, Paris, France

Arsène Mekiniand AP-HP, Hôpital Saint Antoine, service de médecine interne et Inflammation (DHU i2B), Faculté de Médecine Sorbonne Université, Paris, France, Paris, France

Eolia Brissota Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, France

Fella M.’Hammedi-Bouzinaa Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, France

Simona Lapusana Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, France

Mohamad Mohtya Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, France

Karine Lacombee Sorbonne Université, Inserm U1136, Hôpital Saint-Antoine, AP-HP, Paris, France

Patrick Ingilizb Service de Maladies Infectieuses et Tropicales, Saint-Antoine Hospital, Paris, France

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Acknowledgments

AG, TC, PI and KL wrote the manuscript. PB, FM, SL, TC, PI, AM, KL and AG contributed to the acquisition and analysis of the data. TU, JP, AM, EB and MM contributed and revised the manuscript. All authors approved the submitted and final version.

Disclosure statement

EB reports speaker fees from Alexion Pharmaceuticals.

The remaining authors have no actual or potential conflict of interest to declare in relation to this study.

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Severe COVID-19 infection in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab therapy

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Severe COVID-19 infection in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab therapy

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