Acknowledgements
AS analysed the data and wrote the manuscript. VZh designed and performed the experiments. AR assisted in patient recruitment. AR and SP provided the clinical and laboratory data. LP guided clinical care of patients. NM, ES, AM and AP conceived the presented idea and revised the paper critically. All authors discussed the results and approved the final manuscript.
Disclosure statement
No potential conflict of interest was reported by the authors.
Ethical approval
The Ethics Committee of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology approved the study.
Patient consent statement
The participants or their legal guardians signed an informed consent form.