Abstract
A simple device was used to collect milk throughout a lactation from rabbit does. Does were milked everyday (ED), every other day (EOD), or twice a day (2X). Litters and nest boxes were removed from 2X does on day 2 of lactation while litters were present throughout lactation in does milked ED or EOD. Lactation was abruptly terminated in 2X does and the mammary glands involuted between 48 and 60 hours after pup removal. Approximately 600 ml of milk were collected from EOD does while 1400 ml were collected from ED does. The length of lactation was also extended in ED does. The concentration of fat (21 to 24%) and protein (12 to 16%) remained relatively constant throughout lactation. These studies suggest that the rabbit may be an excellent model to study transgenic production of Pharmaceuticals in milk.
Notes
Paper number 3066 of the Mass. Agr. Exp. Sta., Univ. of Mass, at Amherst. This research supported in part by NIH‐SBIR grant no. HD25349‐021A awarded to TSI, Corp., Worcester, MA.