http://orcid.org/0000-0002-2397-8904
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ABSTRACT
In this study, the structural changes of gut microbiota in response to abalone viscera protein hydrolysate (AVPH) were examined in alcohol induced injured mice. The gut microbiota of mice without treatment (blank), alcohol treatment (control), and alcohol+AVPH treatment (sample) were profiled with Illumina sequencing of the V4 region of 16S rDNA genes. The sequencing results revealed that 705, 654, and 888 of Operational Taxonomic Units (OTUs) were determined in the blank, control, and sample groups, respectively. Compared with the control and blank groups, the AVPH had a higher diversity index and a larger number of reads subjecting to Bacilli (class), Lactobacillales (order), Lactobacillaceae (family), and Lactobacillus (genus) levels. However, insignificant difference of beta-diversity or principal component among control, blank, and sample groups was found. This study demonstrates that the in vivo oxidation inhibition pathway in alcohol induced injured mice by AVPH was not via modulating the gut microbiota structure.
Disclosure statement
The authors acknowledge that there is no competing financial interest in the present study.
Funding
This study was supported by the Public Science and Technology Research Funds Projects of Ocean (201405016), the Mega Project of Science Research of Fujian province (2014NZ0001-1), the Special Marine High-Tech Industry Development of Fujian province ([2013]011), the Marine Economy Development Project of Xiamen (14PZY017NF17), and the Marine Economy Innovation and Development Project of Fujian (2014FJPT01).