Fungal Transformations of Steroids by Cephalosporium Aphidicola and Trichothecium Roseum

Atta-Ur-Rahman International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan

M. Iqbal Choudhary International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan

Fahim Asif International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan

Afgan Farooq International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan

M. Yaqoob International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan

Abstract

Transformation of dehydroepiandrosterone (1) was carried out by incubation with the fungus Cephalosporium aphidicola to obtain 3β-hydroxyandrost-4-en-17-one (2) and 3β,4β-dihydroxyandrost-5-en-17-one (3). The fermentation of androsterone (4) by Trichothecium roseum afforded 3α, 17β-dihydroxyandrostane (5).

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Fungal Transformations of Steroids by Cephalosporium Aphidicola and Trichothecium Roseum

Information for

Open access

Opportunities

Help and information

Fungal Transformations of Steroids by Cephalosporium Aphidicola and Trichothecium Roseum

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature